Primary Identifier | IPR026723 | Type | Family |
Short Name | NYAP2 |
description | This entryincludes NYAP2 from neuronal tyrosine-phosphorylated adaptor for the PI 3-kinase (NYAP) family (consisting of NYAP1, NYAP2, NAP3/Myosin16). NYAPs activate phosphoinositide 3-kinase (PI3K) in the PI3K pathway, which is a fundamental pathway for various cellular events in neurons. They also interact with components of the WAVE1 complex, which mediates actin cytoskeleton remodeling through Arp2/3 complex. NYAPs connect PI3K activation to WAVE1 signalling in neurons []. |