First Author | Hildebrand CE | Year | 1985 |
Journal | Somat Cell Mol Genet | Volume | 11 |
Issue | 4 | Pages | 391-5 |
PubMed ID | 3860967 | Mgi Jnum | J:7967 |
Mgi Id | MGI:56436 | Doi | 10.1007/BF01534416 |
Citation | Hildebrand CE, et al. (1985) Assignment of dioxin-inducible cytochrome P-450 gene family to Chinese hamster chromosome 4. Somat Cell Mol Genet 11(4):391-5 |
abstractText | The 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P-450 gene family (P1-450 and P3-450 in the C57BL/6N mouse) has recently been localized to mouse chromosome 9. In the present study, HindIII-digested DNA from Chinese hamster, mouse, and 20 Chinese hamster X mouse somatic cell hybrids and subclones segregating hamster chromosomes was probed with the mouse P1-450 and P3-450 full-length cDNA clones. Hamster P-450 gene fragments (6.0 and 7.4 kb) were assigned to Chinese hamster chromosome 4. These data are consistent with linkage conservation among these two P-450 sequences and four other loci on mouse chromosome 9 that map to hamster chromosome 4. |