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Publication : Assignment of dioxin-inducible cytochrome P-450 gene family to Chinese hamster chromosome 4.

First Author  Hildebrand CE Year  1985
Journal  Somat Cell Mol Genet Volume  11
Issue  4 Pages  391-5
PubMed ID  3860967 Mgi Jnum  J:7967
Mgi Id  MGI:56436 Doi  10.1007/BF01534416
Citation  Hildebrand CE, et al. (1985) Assignment of dioxin-inducible cytochrome P-450 gene family to Chinese hamster chromosome 4. Somat Cell Mol Genet 11(4):391-5
abstractText  The 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P-450 gene family (P1-450 and P3-450 in the C57BL/6N mouse) has recently been localized to mouse chromosome 9. In the present study, HindIII-digested DNA from Chinese hamster, mouse, and 20 Chinese hamster X mouse somatic cell hybrids and subclones segregating hamster chromosomes was probed with the mouse P1-450 and P3-450 full-length cDNA clones. Hamster P-450 gene fragments (6.0 and 7.4 kb) were assigned to Chinese hamster chromosome 4. These data are consistent with linkage conservation among these two P-450 sequences and four other loci on mouse chromosome 9 that map to hamster chromosome 4.
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