Primary Identifier | MGI:5426685 | Allele Type | Targeted |
Attribute String | Conditional ready, Hypomorph, Reporter | Gene | C5ar1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 2. A cassette containing (5' to 3') an IRES, EGFP, SV40 polyadenlyation sequence, FRT-flanked neo cassette and loxP site was inserted into the 3' UTR. FACS analysis confirmed reduction of protein expression in elicited peritoneal neutrophils from homozygous mice. |