Primary Identifier | MGI:2445428 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pitx2 |
Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An allele encoding isoforms a and b, but not the heart- and lung-specific c isoform, was generated by in vivo cre mediated excision of a floxed neo cassette from Pitx2tm3Jfm. The resultant allele contained a single loxP site in place of the c isoform-specific exon 4. |