Primary Identifier | IPR037587 | Type | Family |
Short Name | LAMTOR2-like |
description | This entry represents the Ragulator complex protein LAMTOR2. The Ragulator complex consists of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4 and LAMTOR5 []. The Ragulator complex is involved in amino acid sensing and activation of the mTORC1 signalling pathway. The complex is activated by amino acids through a mechanism involving the lysosomal V-ATPase, and functions as a guanine nucleotide exchange factor activating the small GTPases Rag [], []. This entry also includes uncharacterised proteins from bacteria and archaea. |