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Protein Coding Gene : Rgs5 regulator of G-protein signaling 5

Primary Identifier  MGI:1098434 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  19737
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of vascular associated smooth muscle cell proliferation. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and visual system. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma and essential hypertension. Orthologous to human RGS5 (regulator of G protein signaling 5).
PHENOTYPE: Mice homozygous for a targeted mutation appear normal. [provided by MGI curators]
  • synonyms:
  • regulator of G-protein signaling 5,
  • Rgs5,
  • 1110070A02Rik,
  • MGI:1919050,
  • RIKEN cDNA 1110070A02 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For