| Primary Identifier | MGI:1858952 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 54324 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within several processes, including hematopoietic stem cell homeostasis; myeloid dendritic cell chemotaxis; and positive regulation of podosome assembly. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm and nucleus. Orthologous to human ARHGEF5 (Rho guanine nucleotide exchange factor 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased Th2 response in an ovalbumin-induced asthma model. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
