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Protein Domain : ZW10 interactor

Primary Identifier  IPR029092 Type  Family
Short Name  Zwint-1
description  ZW10 interactor (also known as Zwint-1) is part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity []. It recruits ZW10 to unattached kinetochores at prometaphase []. It is essential for stable binding of a Mad1-Mad2 complex to unattached kinetochores []. It can be phosphoryltated by Aurora B (AurB) kinase [].

0 Child Features

0 Parent Features

4 Protein Domain Regions