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Protein Coding Gene : Pilrb1 paired immunoglobin-like type 2 receptor beta 1

Primary Identifier  MGI:2450532 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  170741
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables MHC class I protein binding activity. Involved in negative regulation of osteoclast differentiation. Acts upstream of or within myeloid dendritic cell activation. Located in plasma membrane. Orthologous to human PILRB (paired immunoglobin like type 2 receptor beta).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased susceptiblity to bacterial infection with S. aureus with decreased worm burden and mortality. [provided by MGI curators]
  • synonyms:
  • Pilrb,
  • paired immunoglobin-like type 2 receptor beta 1,
  • Fdact,
  • paired immunoglobin-like type 2 receptor beta,
  • Pilrb1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For