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Protein Coding Gene : Kif21b kinesin family member 21B

Primary Identifier  MGI:109234 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  16565
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Acts upstream of or within corpus callosum development. Predicted to be located in cell projection; cytoplasmic vesicle; and cytoskeleton. Predicted to be part of kinesin complex. Predicted to be active in microtubule. Is expressed in central nervous system; dorsal root ganglion; and neural retina. Orthologous to human KIF21B (kinesin family member 21B).
PHENOTYPE: Homozygous KO reduces dendrite branching and spine density as a result of reduced microtubule growth, resulting in impaired spatial learning and cued conditioning behavior. [provided by MGI curators]
  • synonyms:
  • Kif21b,
  • mKIAA0449,
  • N-5 kinesin,
  • MGI:2443746,
  • kinesin family member 21B,
  • MGD-MRK-38278,
  • RIKEN cDNA 2610511N21 gene,
  • 2610511N21Rik

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For