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Protein Coding Gene : Clstn2 calsyntenin 2

Primary Identifier  MGI:1929897 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  64085
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable several functions, including X11-like protein binding activity; amyloid-beta binding activity; and kinesin binding activity. Involved in associative learning and inhibitory synapse assembly. Acts upstream of or within positive regulation of synapse assembly and positive regulation of synaptic transmission. Located in cell surface; postsynaptic density; and postsynaptic membrane. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including brain; ear; forelimb bud; heart; and paraxial mesenchyme. Orthologous to human CLSTN2 (calsyntenin 2).
PHENOTYPE: Homozygous KO mice display deficiency in spatial learning and memory in Morris water and Barnes maze tasks and increased locomotor activity in open field test. [provided by MGI curators]
  • synonyms:
  • MGI:1924325,
  • expressed sequence AI448973,
  • CSTN2,
  • RIKEN cDNA 2900042C18 gene,
  • CS2,
  • MGI:2143055,
  • AI448973,
  • calsyntenin 2,
  • 2900042C18Rik,
  • Clstn2,
  • Cst-2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For