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Allele : Dock2<m15Btlr> dedicator of cyto-kinesis 2; mutation 15, Bruce Beutler

Primary Identifier  MGI:6305375 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Dock2
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3512
molecularNote  T to A transversion at base pair 34,503,413 (v38) on chromosome 11, or base pair 269,484 in the GenBank genomic region NC_000077 for the Dock2 gene. The mutation corresponds to residue 2,460 in the mRNA sequence NM_178666 within exon 24 of 52 total exons. The mutation results in a valine to glutamic acid substitution at position 793 (V793E) in the DOCK2 protein
  • mutations:
  • Single point mutation
  • synonyms:
  • wassup,
  • wassup
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele