Primary Identifier | MGI:6305375 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Dock2 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3512 |
molecularNote | T to A transversion at base pair 34,503,413 (v38) on chromosome 11, or base pair 269,484 in the GenBank genomic region NC_000077 for the Dock2 gene. The mutation corresponds to residue 2,460 in the mRNA sequence NM_178666 within exon 24 of 52 total exons. The mutation results in a valine to glutamic acid substitution at position 793 (V793E) in the DOCK2 protein |