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Protein Coding Gene : Ccdc88a coiled coil domain containing 88A
Primary Identifier  MGI:1925177 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  108686
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables microtubule binding activity; protein kinase B binding activity; and protein serine/threonine kinase activator activity. Involved in several processes, including TOR signaling; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of neuron projection development. Located in cell leading edge. Is expressed in several structures, including limb; lung; nervous system; sensory organ; and somite. Orthologous to human CCDC88A (coiled-coil domain containing 88A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal weight loss, reduced angiogenesis, and premature death by P25. [provided by MGI curators]
  • synonyms:
  • MGI:2442608,
  • HkRP1,
  • RIKEN cDNA C330012F17 gene,
  • D130005J21Rik,
  • RIKEN cDNA D130005J21 gene,
  • A430106J12Rik,
  • GIV,
  • coiled coil domain containing 88A,
  • RIKEN cDNA A430106J12 gene,
  • RIKEN cDNA C130096N06 gene,
  • MGI:2443604,
  • MGI:1915538,
  • C330012F17Rik,
  • C130096N06Rik,
  • mKIAA1212,
  • Ccdc88a,
  • expressed sequence AI848406,
  • MGI:2144295,
  • Girdin,
  • AI848406
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1 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Function

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Homology

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6 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

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