Primary Identifier | MGI:97919 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 19752 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable RNA nuclease activity. Acts upstream of or within response to bacterium. Predicted to be located in extracellular region. Is expressed in several structures, including alimentary system; brain; integumental system; limb segment; and reproductive system. Orthologous to human RNASE1 (ribonuclease A family member 1, pancreatic). PHENOTYPE: Mice homozygous for a null allele exhibit increased weight, quickler plasma clotting and elevated FXII and FXI activity. [provided by MGI curators] |