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Allele : Ppp2r1a<tm2.1Wltr> protein phosphatase 2, regulatory subunit A, alpha; targeted mutation 2.1, Gernot Walter

Primary Identifier  MGI:5287375 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Ppp2r1a
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was related with a modified exon 3 in which nucleotide substitution (GAG to GAC) results in the amino acid substitution of aspartic acid for glutamic acid at position 64 (E64D), mimicking a mutation found in a human lung carcinoma. A floxed neo cassette inserted downstream of the modified exon 3 was removed by cre-mediated recombination.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • PP2A-A-alpha-E64D,
  • PP2A-A-alpha-E64D
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele