Primary Identifier | MGI:1925903 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 78653 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to be involved in protein maturation by [4Fe-4S] cluster transfer. Predicted to be located in cytosol; mitochondrion; and nuclear body. Predicted to be part of iron-sulfur cluster assembly complex. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 2. Orthologous to human BOLA3 (bolA family member 3). PHENOTYPE: Mice in which the gene is deleted in fat tissue, show impaired glucose tolerance, impaired norepinephrine-induced brown adipose tissue thermogenesis, increased weight gain at thermoneutral temperature and decreased brown adipose tissue glucose uptake [provided by MGI curators] |