| Primary Identifier | MGI:1914291 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 67041 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables succinyl-CoA:3-oxo-acid CoA-transferase activity. Acts upstream of or within ketone body catabolic process and ketone catabolic process. Located in mitochondrion. Is expressed in foregut and heart. Orthologous to human OXCT1 (3-oxoacid CoA-transferase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit hyperketonemia, ketoacidosis, increased glucose oxidation in the brain, increased autophagy in the brain, and neonatal lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
