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Protein Coding Gene : Suclg2 succinate-Coenzyme A ligase, GDP-forming, beta subunit

Primary Identifier  MGI:1306824 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  20917
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable GDP binding activity; succinate-CoA ligase (GDP-forming) activity; and succinate-semialdehyde dehydrogenase (NAD+) activity. Predicted to be involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Part of succinate-CoA ligase complex (GDP-forming). Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SUCLG2 (succinate-CoA ligase GDP-forming subunit beta).
PHENOTYPE: Homozygous knockout with a gene trap is embryonic lethal. Heterozygosity has a mild effect on mitochondrial respiration. [provided by MGI curators]
  • synonyms:
  • D6Wsu120e,
  • expressed sequence AW556404,
  • expressed sequence AF171077,
  • DNA segment, Chr 6, Wayne State University 120, expressed,
  • AF171077,
  • succinate-Coenzyme A ligase, GDP-forming, beta subunit,
  • MGD-MRK-35775,
  • AW556404,
  • MGI:107309,
  • MGI:2141376,
  • MGI:2141706,
  • Suclg2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For