| Primary Identifier | MGI:3051150 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(TcraTcrb)8Rest |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | These coinjected transgenes encode an H2-Db-restricted Valpha1 Vbeta13 T-cell receptor that recognizes a peptide comprising amino acids 25-33 of the protein known as pmel-17/gp100, a pigment biosynthetic enzyme that is encoded by the mouse Si (silver) gene and is expressed both in normal melanocytes and in malignant melanoma. The insertion is accompanied by a 157-bp deletion (chr2: 68,208,872?68,209,029 bp - build unknown). |
