| Primary Identifier | IPR016153 | Type | Homologous_superfamily |
| Short Name | Heat_shock_Hsp33_N |
| description | This superfamily represents the N-terminal, 3-layer beta/alpha/beta domain from the heat shock protein Hsp33. Hsp33 is a molecular chaperone, distinguished from all other known chaperones by its mode of functional regulation. Its activity is redox regulated. Hsp33 is a cytoplasmically localised protein with highly reactive cysteines that respond quickly to changes in the redox environment. Oxidizing conditions like H2O2cause disulphide bonds to form in Hsp33, a process that leads to the activation of its chaperone function []. |
