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Allele : G6pc2<tm1.1Pesa> glucose-6-phosphatase, catalytic, 2; targeted mutation 1.1, Pere Santamaria

Primary Identifier  MGI:4461063 Allele Type  Targeted
Gene  G6pc2 Transmission  Germline
Strain of Origin  129S2/SvPas Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 5 was replaced with an frt flanked neo cassette and a modified exon 5 in which nucleotide substitutions result in the amino acid substitutions of alanine for lysine at position 209 (K209A) and alanine for phenylalanine at position 213 (F213A). Flp mediated recombination removed the neo cassette leaving a single frt site downstream of the modified exon 5. The modified residues participate in T cell receptor contact.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • IGRP<K209A/F213A-KI>,
  • IGRP<K209A/F213A-KI>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele