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Allele : Dpp8<tm1.1Npa> dipeptidylpeptidase 8; targeted mutation 1.1, Novartis Pharma AG
Primary Identifier  MGI:6157524 Allele Type  Targeted
Attribute String  Not Specified Gene  Dpp8
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 18 was replaced with a modified on in which nucleotide substitutions result in the amino acid substitution of alanine for serine at position 749 (S749A). This mutation is predicted to cause the loss of enzyme activity. Flp-mediated recombination removed an FRT-flanked neomycin resistance cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Dpp8<ki>,
  • Dpp8<ki>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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