| Primary Identifier | MGI:1346882 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 26411 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; liver; and lung. Orthologous to human MAP4K1 (mitogen-activated protein kinase kinase kinase kinase 1). PHENOTYPE: Homozygous null mice have increased responses of B and T cells. Dendritic cells are also hyperresponsive to stimulation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
