Primary Identifier | MGI:5460881 | Allele Type | Chemically induced (ENU) |
Gene | Hbb-b1 | Inheritance Mode | Dominant |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | ENU induced a C to T substitution at nucleotide position 118 that is predicted to result in a nonsense mutation (Q40X) in exon 2. Q-PCR on RNA from fetal liver cells indicates that transcript expression is reduced in homozygotes and heterozygotes. |