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Protein Coding Gene : Zcchc8 zinc finger, CCHC domain containing 8

Primary Identifier  MGI:1917900 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  70650
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable RNA binding activity. Predicted to be involved in RNA processing. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nuclear body. Predicted to be part of TRAMP complex and catalytic step 2 spliceosome. Is expressed in several structures, including blastocyst; early embryo; eye; secondary oocyte; and trunk somite. Orthologous to human ZCCHC8 (zinc finger CCHC-type containing 8).
PHENOTYPE: Mice homozygous for a null allele show partial lethality by E17.5 and lower survival rate in the first 3 months, small body size, infertility, small testes and ovaries, loss of sperm, fewer mature ovarian follicles, and oocyte maturation defects. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 5730565F05 gene,
  • Zcchc8,
  • 5730565F05Rik,
  • zinc finger, CCHC domain containing 8

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For