Primary Identifier | MGI:1917900 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 70650 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable RNA binding activity. Predicted to be involved in RNA processing. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nuclear body. Predicted to be part of TRAMP complex and catalytic step 2 spliceosome. Is expressed in several structures, including blastocyst; early embryo; eye; secondary oocyte; and trunk somite. Orthologous to human ZCCHC8 (zinc finger CCHC-type containing 8). PHENOTYPE: Mice homozygous for a null allele show partial lethality by E17.5 and lower survival rate in the first 3 months, small body size, infertility, small testes and ovaries, loss of sperm, fewer mature ovarian follicles, and oocyte maturation defects. [provided by MGI curators] |