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Protein Coding Gene : Celf4 CUGBP, Elav-like family member 4

Primary Identifier  MGI:1932407 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  108013
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables mRNA binding activity. Acts upstream of or within several processes, including mRNA splice site recognition; negative regulation of excitatory postsynaptic potential; and negative regulation of mRNA splicing, via spliceosome. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; gonad; mammary gland; and retina. Orthologous to human CELF4 (CUGBP Elav-like family member 4).
PHENOTYPE: Mice homozygous for a null allele exhibit neonatal lethality, shortened life span dependent on genetic background, and seizures. Mice heterozygous for a null allele exhibit complex seizures and abnormal body weights depending on age. [provided by MGI curators]
  • synonyms:
  • Brul4,
  • Brunol4,
  • RIKEN cDNA C130060B05 gene,
  • Celf4,
  • A230070D14Rik,
  • bruno-like 4, RNA binding protein (Drosophila),
  • MGI:2444528,
  • CUGBP, Elav-like family member 4,
  • MGI:2442678,
  • C130060B05Rik,
  • BRUNOL-4,
  • RIKEN cDNA A230070D14 gene

Features --> Cross References

Genome

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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1 Driver For