| Primary Identifier | IPR033606 | Type | Family |
| Short Name | Hemojuvelin |
| description | Hemojuvelin, also called repulsive guidance molecule C or Hfe2, is a GPI-linked membrane protein essential for iron homeostasis []. Hemojuvelin is a bone morphogenetic protein (BMP) coreceptor; it regulates iron homeostasis by interacting with BMP ligands to induce hepcidin expression []. It forms a membrane-associated protein complex with HFE and the transferrin receptor 2 for hepcidin regulation []. |
