| First Author | Gubbay J | Year | 1992 |
| Journal | Proc Natl Acad Sci U S A | Volume | 89 |
| Issue | 17 | Pages | 7953-7 |
| PubMed ID | 1518820 | Mgi Jnum | J:2258 |
| Mgi Id | MGI:50782 | Doi | 10.1073/pnas.89.17.7953 |
| Citation | Gubbay J, et al. (1992) Inverted repeat structure of the Sry locus in mice. Proc Natl Acad Sci U S A 89(17):7953-7 |
| abstractText | The testis-determining gene Sry is located on the short arm of the mouse Y chromosome in a region known to have undergone duplications and rearrangements in comparison with the equivalent portion of the human Y chromosome. Detailed analysis of the Sry genomic locus reveals a further difference in that the mouse Sry open reading frame lies within 2.8 kilobases of unique sequence at the center of a large inverted repeat. This repeat, which is found in both Mus musculus musculus and Mus musculus domesticus Y chromosomes, is not present at the human SRY locus. Recombination involving the repeat region may have led to an 11-kilobase deletion, precisely excising Sry in a line of XY female mice. |
