Primary Identifier | MGI:3615340 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Dsc3 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed PGK-neo cassette replaced part of the promoter, exon 1 (containing the start codon) and intron 1. Quantitative PCR and Western blot analysis demonstrated that expression in heterozygous mice is half that of wild-type mice. |