Primary Identifier | MGI:1347086 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 26369 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables G-protein beta/gamma-subunit complex binding activity; heterotrimeric G-protein binding activity; and microtubule binding activity. Acts upstream of or within cellular response to heat. Located in centrosome and photoreceptor connecting cilium. Is expressed in embryo; inner cell mass; and photoreceptor layer. Orthologous to human CETN1 (centrin 1). PHENOTYPE: Mice homozygous for a knock-out allele show male infertility associated with oligozoospermia, teratozoospermia, immotile sperm, and altered centriole rearrangement at a late stage of spermiogenesis. [provided by MGI curators] |