First Author | Kemp SJ | Year | 1996 |
Journal | Vet Immunol Immunopathol | Volume | 54 |
Issue | 1-4 | Pages | 239-43 |
PubMed ID | 8988870 | Mgi Jnum | J:98907 |
Mgi Id | MGI:3580722 | Doi | 10.1016/s0165-2427(96)05692-9 |
Citation | Kemp SJ, et al. (1996) Genetic control of resistance to trypanosomiasis. Vet Immunol Immunopathol 54(1-4):239-43 |
abstractText | To map the genetic sources of trypanotolerance in mice, a linkage analysis of survival following trypanosome challenge was performed by selective genotyping in a large F2 population produced by crossing the resistant C57BL/6 and susceptible BALB/c inbred mouse lines. We report evidence of a chromosomal region of large effect, possibly comprising more than one resistance locus, on Chromosome 17; and of further loci on Chromosomes 1 and 5. Together, these genes can account for all of the difference between the mean parental phenotypes. |