| Primary Identifier | MGI:87926 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 11529 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables all-trans-retinol dehydrogenase (NAD+) activity. Acts upstream of or within ethanol catabolic process; retinoic acid metabolic process; and retinol metabolic process. Predicted to be located in plasma membrane. Predicted to be active in cytosol. Is expressed in several structures, including branchial arch; embryo mesenchyme; endocrine gland; genitourinary system; and neural fold. Used to study Parkinson's disease. Orthologous to human ADH7 (alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide). PHENOTYPE: Homozygous mutation of this gene results in defective ethanol clearance and reduced metabolism of retinal to retinoic acid. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
