| First Author | Kwon BS | Year | 1989 |
| Journal | Proc Natl Acad Sci U S A | Volume | 86 |
| Issue | 6 | Pages | 1963-7 |
| PubMed ID | 2784565 | Mgi Jnum | J:14661 |
| Mgi Id | MGI:62825 | Doi | 10.1073/pnas.86.6.1963 |
| Citation | Kwon BS, et al. (1989) cDNA sequences of two inducible T-cell genes. Proc Natl Acad Sci U S A 86(6):1963-7 |
| abstractText | We have previously described a set of human T-lymphocyte-specific cDNA clones isolated by a modified differential screening procedure. Apparent full-length cDNAs containing the sequences of 14 of the 16 initial isolates were sequenced and were found to represent five different species of mRNA; three of the five species were identical to previously reported cDNA sequences of preproenkephalin, T-cell-replacing factor, and a serine esterase, respectively. The other two species, 4-1BB and L2G25B, were inducible sequences found in mRNA from both a cytolytic T-lymphocyte and a helper T-lymphocyte clone and were not previously described in T-cell mRNA; these mRNA sequences encode peptides of 256 and 92 amino acids, respectively. Both peptides contain putative leader sequences. The protein encoded by 4-1BB also has a potential membrane anchor segment and other features also seen in known receptor proteins. |
