| Primary Identifier | MGI:3522703 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(HK2-luc)242Uku |
| Strain of Origin | (BALB/c x DBA/2)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | No distinction was made between this transgenic line and Tg(HK2-luc)237Uku, which carries 7-9 copies of the same construct; the authors state there were no significant differences between them, whether or not results were normalized to copy number. It was noted that baseline luciferase expression varied inversely with transgene copy number. Basal luciferase activity in heart, skeletal muscle and adipose tissue of 4 to 5-week old transgenic mice was at background level. |
| molecularNote | This transgenic line carries 200-220 copies of a construct comprising 97 base pairs of 5' flanking DNA and 106 base pairs of untranslated sequence from exon I of the human hexokinase II gene joined to the firefly luciferase coding sequence, which is followed by the SV40 small intron and polyadenylation signal. |
