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Publication : Genomic structure, promoter sequence, and revised translation of human homeobox gene HLX1.

First Author  Kennedy MA Year  1994
Journal  Genomics Volume  22
Issue  2 Pages  348-55
PubMed ID  7806220 Mgi Jnum  J:19672
Mgi Id  MGI:67812 Doi  10.1006/geno.1994.1394
Citation  Kennedy MA, et al. (1994) Genomic structure, promoter sequence, and revised translation of human homeobox gene HLX1. Genomics 22(2):348-55
abstractText  The human homeobox gene HLX1 appears to be involved in hemopoietic development and may represent a candidate gene for various developmental or hemopoietic disorders. We have isolated genomic clones for the gene, determined its intron-exon organization, and confirmed its map location on chromosome 1q41-q42. The transcription initiation sites of HLX1 were identified, and DNA sequences upstream of these sites were established. Finally, several differences between the genomic sequence and the published cDNA sequence were noted. Translation based on this revised sequence gives rise to a putative protein with 86.5% homology to the product of the murine Hlx gene.
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