| Primary Identifier | MGI:102850 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 16612 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides and serine-type endopeptidase activity. Predicted to be involved in regulation of systemic arterial blood pressure and zymogen activation. Predicted to be located in several cellular components, including acrosomal vesicle; apical part of cell; and extracellular space. Predicted to be part of protein-containing complex. Predicted to be active in secretory granule. Is expressed in several structures, including early conceptus; female reproductive system; and salivary gland. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1). |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
