| First Author | Tilson MD | Year | 1995 |
| Journal | Biochem Biophys Res Commun | Volume | 213 |
| Issue | 1 | Pages | 40-3 |
| PubMed ID | 7639759 | Mgi Jnum | J:27981 |
| Mgi Id | MGI:75615 | Doi | 10.1006/bbrc.1995.2095 |
| Citation | Tilson MD (1995) Similarities of an autoantigen in aneurysmal disease of the human abdominal aorta to a 36-kDa microfibril-associated bovine aortic glycoprotein. Biochem Biophys Res Commun 213(1):40-3 |
| abstractText | Immunoglobulin G (IgG) from human aneurysmal aorta was used to partially purify an aortic protein with an apparent MW approximately 80 kDa. Amino acid sequencing of a tryptic digest revealed two sequences with homology to mouse tenascin-X. The autoimmune IgG was then shown to react with purified human tenascin, and a rabbit polyclonal anti-human tenascin antibody was found to react with the purified autoantigen. These observations suggest that the autoantigen of abdominal aortic aneurysm disease may be homologous to a calcium-binding member of the tenascin superfamily that has been identified by others in pig and cow. |
