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Publication : Emerging from NF-κB's shadow, SUMOylated IκBα represses transcription.

First Author  Perkins ND Year  2013
Journal  Cancer Cell Volume  24
Issue  2 Pages  139-40
PubMed ID  23948292 Mgi Jnum  J:202614
Mgi Id  MGI:5520118 Doi  10.1016/j.ccr.2013.07.011
Citation  Perkins ND (2013) Emerging from NF-kappaB's shadow, SUMOylated IkappaBalpha represses transcription. Cancer Cell 24(2):139-40
abstractText  In this issue of Cancer Cell, Mulero and colleagues describe an NF-kappaB independent transcriptional repression function for SUMOylated IkappaBalpha. This compelling and provocative model links IkappaBalpha to the activity of the Polycomb repressors and provides a mechanism to link inflammatory signaling to skin homeostasis.
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