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Allele : Gabra2<C57BL/6J+em1Geh> gamma-aminobutyric acid type A receptor subunit alpha 2; endonuclease-mediated revertant 1, Gregg E Homanics
Primary Identifier  MGI:6381661 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Gabra2
Inheritance Mode  Dominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 was used to insert a single base pair (A on negative strand) between Chr5:71,014,638-639 to correct the spontaneous deletion of an A in intron 4 that is inherent in C57BL/6J and BXD40. This restores the allele to the "wild-type" form as found in C57BL/6NJ, C57BL/6ByJ, C57BL/6EiJ, DBA/2J and others.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Rr126<C57BL/6J+em1Geh>,
  • Gabra2<KI>,
  • Gabra2<KI>,
  • Gabra2<em1Geh>,
  • Gabra2<em1Geh>,
  • Rr126<C57BL/6J+em1Geh>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




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