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Publication : IL-10 control of dendritic cells in the skin.

First Author  Clausen BE Year  2013
Journal  Oncoimmunology Volume  2
Issue  3 Pages  e23186
PubMed ID  23802070 Mgi Jnum  J:205537
Mgi Id  MGI:5545715 Doi  10.4161/onci.23186
Citation  Clausen BE, et al. (2013) IL-10 control of dendritic cells in the skin. Oncoimmunology 2(3):e23186
abstractText  Interleukin-10 (IL-10) is a potent immunomodulatory cytokine, whose cellular targets have not yet been precisely identified. Dendritic cell (DC)-specific IL-10 receptor knockout mice exhibit exaggerated T-cell reactivation in the skin, highlighting a key role of DCs in the maintenance of local immune homeostasis, beyond their classical function as regulators of T-cell priming in lymph nodes.
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