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Protein Coding Gene : Alpk1 alpha-kinase 1

Primary Identifier  MGI:1918731 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  71481
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable monosaccharide binding activity and protein serine/threonine kinase activity. Involved in cytoplasmic pattern recognition receptor signaling pathway and innate immune response. Acts upstream of or within response to bacterium. Located in photoreceptor connecting cilium. Orthologous to human ALPK1 (alpha kinase 1).
PHENOTYPE: Homozygosity for the p.T237M mutation leads to increased levels of certain chemokines. [provided by MGI curators]
  • synonyms:
  • Alpk1,
  • 8430410J10Rik,
  • alpha-kinase 1,
  • RIKEN cDNA 8430410J10 gene

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

24 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For