| Primary Identifier | MGI:106095 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 17938 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables TBP-class protein binding activity and transcription coactivator activity. Involved in several processes, including negative regulation of striated muscle cell apoptotic process; positive regulation of skeletal muscle tissue growth; and regulation of transcription by RNA polymerase II. Acts upstream of or within myoblast migration. Located in cytoplasm and nucleus. Is expressed in several structures, including aorta; genitourinary system; gut; liver; and spleen. Orthologous to human NACA (nascent polypeptide associated complex subunit alpha). PHENOTYPE: Mice homozygous for a point mutation exhibit decreased bone volume and bone formation associated with accelerated mineralization and immature woven-bone formation. Mice null for the muscle specific isoform die during organogenesis with cardiac abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
