|  Help  |  About  |  Contact Us

Allele : Rr175<tm1.1Mema> regulatory region 175; targeted mutation 1.1, Masatsugu Ema
Primary Identifier  MGI:5304851 Allele Type  Targeted
Attribute String  Hypomorph, Modified regulatory region Gene  Rr175
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A LoxP and FRT ste flanked neomycin resistance gene cassette replaced the Distal Multipotent Mesodermal Enhancer (DMME), located 27 kb upstream of the TSS of the Kdr gene, via homologous recombination. Cre-mediated recombination removed the neo cassette. Quantitative RT-PCR and immunohistochemical analyses indicate that expression is reduced at E7.5 in homozygous embryos.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Kdr<tm1.1Mema>,
  • Kdr<tm1.1Mema>,
  • Flk1-DMME KO,
  • Flk1-DMME KO
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom