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Protein Coding Gene : Zbtb22 zinc finger and BTB domain containing 22

Primary Identifier  MGI:1931870 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  81630
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and liver. Orthologous to human ZBTB22 (zinc finger and BTB domain containing 22).
PHENOTYPE: Mice homozygous for a null allele show protection from high-fat diet induced obesity, showing improved energy expenditure, glucose tolerance, and insulin sensitivity and reduced hepatic steatosis. [provided by MGI curators]
  • synonyms:
  • zinc finger and BTB domain containing 22,
  • MGI:2146815,
  • zinc finger protein 297,
  • expressed sequence AI415166,
  • 1110008J20Rik,
  • Bing1,
  • MGI:1920984,
  • AI415166,
  • RIKEN cDNA 1110008J20 gene,
  • expressed sequence AI265210,
  • Zfp297,
  • AI265210,
  • Zbtb22,
  • MGI:2146842

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Canonical gene --> CDSs in specific strains.

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Canonical gene --> Transcripts in specific strains.

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