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Protein Coding Gene : Arfgef3 ARFGEF family member 3

Primary Identifier  MGI:106387 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  215821
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Predicted to be located in cytoplasmic vesicle and membrane. Is expressed in central nervous system; dorsal root ganglion; and sensory organ. Orthologous to human ARFGEF3 (ARFGEF family member 3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased insulin granule biogenesis and insulin secretion. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-34080,
  • D10Bwg1379e,
  • Arfgef3,
  • MGI:3029309,
  • mKIAA1244,
  • DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed,
  • ARFGEF family member 3,
  • B930094H20Rik,
  • RIKEN cDNA B930094H20 gene,
  • BIG3

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For