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Protein Coding Gene : Gadd45gip1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
Primary Identifier  MGI:1914947 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  102060
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables mitochondrial ribosome binding activity. Acts upstream of or within positive regulation of cell population proliferation and positive regulation of oxidative phosphorylation. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; intestine epithelium; and secondary oocyte. Used to study type 2 diabetes mellitus. Orthologous to human GADD45GIP1 (GADD45G interacting protein 1).
PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality before somite formation with decreased cell proliferation, increased apoptisis, and failure of inner cell mass outgrowth. [provided by MGI curators]
  • synonyms:
  • growth arrest and DNA-damage-inducible, gamma interacting protein 1,
  • 2310040G17Rik,
  • RIKEN cDNA 2310040G17 gene,
  • expressed sequence AI425883,
  • Crif1,
  • Gadd45gip1,
  • AI425883,
  • MGI:2142529
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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