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Protein Coding Gene : Mug1 murinoglobulin 1

Primary Identifier  MGI:99837 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  17836
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable endopeptidase inhibitor activity and protease binding activity. Acts upstream of or within embryo implantation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in liver. Orthologous to human PZP (PZP alpha-2-macroglobulin like).
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and phenotypically normal under standard conditions but show increased mortality in response to diet-induced acute pancreatitis along with hepatic cell necrosis and inflammatory infiltration, andincreased plasma amylase and lipase levels. [provided by MGI curators]
  • synonyms:
  • murinoglobulin 1,
  • Mug1,
  • MGD-MRK-16627

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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