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Protein Coding Gene : Srgap1 SLIT-ROBO Rho GTPase activating protein 1
Primary Identifier  MGI:2152936 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  117600
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables GTPase activator activity and small GTPase binding activity. Acts upstream of or within Rho protein signal transduction and cell migration. Predicted to be active in cytoplasm. Is expressed in nervous system and s-shaped body. Used to study focal segmental glomerulosclerosis. Human ortholog(s) of this gene implicated in thyroid gland papillary carcinoma. Orthologous to human SRGAP1 (SLIT-ROBO Rho GTPase activating protein 1).
  • synonyms:
  • 4930572H05Rik,
  • Srgap1,
  • RIKEN cDNA 4930572H05 gene,
  • SLIT-ROBO Rho GTPase activating protein 1,
  • MGI:1914994,
  • Arhgap13
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Canonical gene --> Transcripts in specific strains.

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7 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

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