| Primary Identifier | MGI:101940 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 11857 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable GTPase activity; Rho GDP-dissociation inhibitor activity; and small GTPase binding activity. Predicted to be involved in Rho protein signal transduction; negative regulation of trophoblast cell migration; and regulation of Rho protein signal transduction. Predicted to be located in cytoplasm. Predicted to be active in cytosol and membrane. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and yolk sac. Orthologous to human ARHGDIB (Rho GDP dissociation inhibitor beta). PHENOTYPE: A homozygous null mutation results in mice that are viable and fertile. Immune responses are similar to controls in mice, but in vitro analysis demonstrated an increased B cell proliferative response upon lectin stimulation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
