First Author | Komori T | Year | 1998 |
Journal | Curr Opin Genet Dev | Volume | 8 |
Issue | 4 | Pages | 494-9 |
PubMed ID | 9729728 | Mgi Jnum | J:49453 |
Mgi Id | MGI:1277498 | Doi | 10.1016/s0959-437x(98)80123-8 |
Citation | Komori T, et al. (1998) Cbfa1 in bone development. Curr Opin Genet Dev 8(4):494-9 |
abstractText | A factor fundamental to bone formation has been identified. Gene targeting shows that core-binding factor alpha 1 (Cbfa1) plays an essential role in bone formation and osteoblast differentiation. Thus, it is now possible to begin examining the molecular mechanism of bone formation--especially osteoblast differentiation. |